Say it ain't so, Floyd
Landis is said to have tested positive for testosterone doping after winning stage 17, specifically, that his T/E ratio exceeded the criteria of 4:1. Testosterone doping is difficult to detect, since the body naturally produces testosterone, and the levels vary day to day and from individual to individual. This test attempts to circumvent those problems by comparing the level of testosterone to another hormone in the body. If an athlete is taking testosterone, there will be elevated levels compared to other hormones in his blood, although there are many simple methods to overcome this effect, such as using a patch to deliver the testosterone in continuous doses, and by removing the patch as little as an hour before testing will eliminate the discrepancy. Another test attempts to detect testosterone that was not produced by the athlete, and although it's not clear, experts believe that Landis has the right to request this test on the B sample. This test, called IRMS (isotope ratio mass spectrometry), performs carbon isotope analyses to differentiate natural and synthetic steroids. Of course, by storing your own body's testosterone, this test could be faked out as well.
This article in Velo News summarizes the issues so far.
This article from the New Yorker discusses performance-enhancing testing and athletes (see section 3 for specifics about T/E testing)
This blog is written by a graduate school reasearcher and gives a great deal of technical information about the types of testing.
Observations
1) The lab that performed the test and leaked the information to the media is the same French lab that leaked the false reports that Lance Armstrong's 1999 samples had tested positive for doping.
2) Landis was tested six times previously during the race, and none of these tests indicated testosterone doping. Many experts are saying it would be impossible to create that drastic a change in levels by taking testosterone.
3) There have been many, many criticisms of this test previous to this incident, and every cyclist who has challenged a positive result in this test has prevailed
4) Many experts have indicated that other factors could produce these effects, including Landis' (legal) cortisone shots, alcohol use, and Landis' thyroid problems. Other factors can cause swings in the ratio, such as dehydration, fatigue, diet, and depletion of reserves over the 21 day race.
5) Even if the additional testing indicates that Landis is not guilty of doping, the Federation could still impose the same penalty for testing positive based on the original test
6) If Landis is disqualified, Oscar Pereiro will be crowned as Tour winner. Andreas Klöden (T-Mobile) be second and Carlos Sastre (CSC) would move up from fourth to a podium spot
7) If Landis is disqualified, it would be the first doping-related disqualification in Tour history, which says something about either the efficacy The top four finishers of the 1904 Tour were disqualified for cheating, but because they didn't ride the entire course.
Read more in my series on the 2006 Tour de France:
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